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Publications 2005-2008


Publications of the Nanotechnology for Life Science Group 2005-2008.



2008

Z. Zarafshani, O. Akdemir, J.-F. Lutz, A “click” Strategy for Tuning in situ the Hydrophilic-Hydrophobic Balance of AB Macrosurfactants, submitted to Macromolecular Rapid Communications, invited article for the special issue on “click” chemistry.

J.-F. Lutz, J. Andrieu, A. Hoth, S. Agarwal, Synthesis of Biorelevant Polymers by Controlled Radical Polymerization, submitted as a Polymer Preprints (American Chemical Society, Division of Polymer Chemistry).

E. Wischerhoff, K. Uhlig, A. Lankenau, H.G. Börner, A. Laschewsky, C. Duschl, J.-F. Lutz, Controlled Cell Adhesion on PEG-based Switchable Surfaces, Angewandte Chemie International Edition, in press.

J.-F. Lutz, Z. Zarafshani, Efficient Construction of Therapeutics, Bioconjugates, Biomaterials and Bioactive Surfaces using Azide-Alkyne "click" Chemistry, Advanced Drug Delivery Reviews, invited review, in press - available online.

J.-F. Lutz, Polymerization of Oligo(ethylene glycol) (Meth)acrylates: Toward New Generations of Smart Biocompatible Materials, Invited highlight, Journal of Polymer Science, Part A: Polymer Chemistry, 46, 3459-3470 (2008)

J.-F. Lutz, Copper-Free Azide-Alkyne Cycloadditions: New Insights and Perspectives, Angewandte Chemie International Edition, 47, 2182-2184 (2008).

J. Hentschel, K. Bleek, O. Ernst, J.-F. Lutz, H.G. Börner, Easy Access to Bioactive Peptide-polymer Conjugates via RAFT, Submitted to Macromolecules, 41, 1073-1075 (2008).

J.-F. Lutz, H. Schlaad, Modular Chemical Tools for Advanced Macromolecular Engineering, invited feature article, Polymer, 49, 817-824 (2008)

J.-F. Lutz, K. Weichenhan, O. Akdemir, Z. Zarafshani, Modern Toolbox for Macromolecular Design: Dual-Platform ATRP + Copper Catalyzed [3+2] Huisgen Cycloadditions, Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 49, 186-187 (2008).

J.-F. Lutz, E. Ortel, Development of PEGylated Organic-Inorganic Hybrids as Potential Contrast Agents for Medical Imaging, PMSE Preprints (American Chemical Society, Division of Polymeric Materials: Science and Engineering Preprints), 98, 289-290 (2008).

J.-F. Lutz, Synthesis and Applications of PEG-based Stimuli-Responsive Materials, Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 49, 1076 (2008).

J.-F. Lutz, H.G. Börner, Modern Trends in Polymer Bioconjugates Design, Progress in Polymer Science, 33, 1-39 (2008)


2007

J.-F. Lutz, S. Pfeifer, Z. Zarafshani, In situ Functionalization of Thermoresponsive Polymeric Micelles using the "click" Cycloaddition of Azides and Alkynes, QSAR & combinatorial science, 26, 1151-1158 (2007). Invited article for the special issue on "click" chemistry.

J.-F. Lutz, J. Andrieu, S. Üzgün, C. Rudolph, S. Agarwal, Biocompatible, Thermoresponsive, and Biodegradable: Simple Preparation of "all-in-one" Biorelevant Polymers, Macromolecules, 40, 8540-8543 (2007)

S. Pfeifer, J.-F. Lutz, A Facile Procedure for Controlling Sequences in Chain Polymerizations, Journal of the American Chemical Society, 129, 9542-9543 (2007)

J.-F. Lutz, H.G. Börner, K. Weichenhan, "Click" Bioconjugation of a Well-defined Synthetic Polymer and a Protein Transduction Domain, Invited article for the Research front: "click" chemistry in polymer synthesis, Australian Journal of Chemistry, 60, 410-413 (2007)

J.-F. Lutz, S. Geffroy, H. von Berlepsch, C. Böttcher, S. Garnier, A. Laschewsky, Investigation of a Dual-set of Driving-forces (Hydrophobic + Electrostatic) for the Two-step Fabrication of Defined Block-Copolymer Micelles, Soft Matter, 3, 694-698 (2007)

J.-F. Lutz, K. Weichenhan, O. Akdemir, A. Hoth, About Phase Transitions in Aqueous Solutions of Thermoresponsive Copolymers and Hydrogels based on 2-(2-methoxyethoxy)ethyl Methacrylate and Oligo(ethylene glycol) Methacrylate, Macromolecules, 40, 2503-2508 (2007)

J.-F. Lutz, 1,3-Dipolar Cycloaddition of Azides and Alkynes: A Universal Ligation Tool in Polymer and Materials Science, Angewandte Chemie International Edition, 46, 1018-1025 (2007)

K. Skrabania, J. Kristen, A. Laschewsky, O. Akdemir, A. Hoth, J.-F. Lutz, Aqueous Aggregation Behavior of Non-ionic Single and Multiple Thermoresponsive Polymers, Langmuir, 23, 84-93 (2007)


2006

J.-F. Lutz, S. Stiller, A. Hoth, L. Kaufner, U. Pison, R. Cartier, One-pot Synthesis of PEGylated Ultrasmall Iron-oxide Nanoparticles and their in vivo Evaluation as Magnetic Resonance Imaging Contrast Agents, biomacromolecules, 7, 3132-3138 (2006)

J.-F. Lutz, O. Akdemir, A. Hoth, Point by Point Comparison of Two Thermosensitive Polymers Exhibiting a Similar LCST: is the Age of Poly(NIPAM) Over ? Journal of the American Chemical Society, 128, 13046-13047 (2006)

S. Acerbis, D. Bertin, B. Boutevin, D. Gigmes, P. Lacroix-Desmazes, C. Le Mercier, J.-F. Lutz, S. R. A. Marque, D. Siri, P. Tordo, Intramolecular Hydrogen Bonding: The Case of b-Phosphorylated Aminoxyl Radical. Hydrogen Bonding and Electrostatic Stabilizing Interactions, Helvetica Chimica Acta, Special issue in memory of professor Hanns Fischer, 89, 2119-2132 (2006)

J.-F. Lutz, H.G. Boerner, K. Weichenhan, “Combining ATRP and “click” chemistry: a Promising Platform Towards Functional Biocompatible Polymers and Polymer Bioconjugates”, Macromolecules, 39, 6376-6383 (2006)

J.-F. Lutz, J. Kristen, K. Skrabania, A. Laschewsky, “Synthetic Strategies for Preparing Multicompartment Micelles”, Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 47, 792-793 (2006)

J.-F. Lutz, O. Akdemir, A. Hoth, “New Perspectives in PEGylation: Controlled Radical Polymerization of Oligo(ethylene glycol) Methacrylates”, PMSE Preprints (American Chemical Society, Division of Polymeric Materials: Science and Engineering Preprints), 95, 1052-1053 (2006)

J.-F. Lutz, S. Pfeifer, M. Chanana, A.F. Thünemann, R. Bienert, “H-bonding Directed Self-Assembly of Synthetic Copolymers Containing Nucleobases: Organization and Colloidal Fusion in a Non-competitive Solvent”, Langmuir, 22, 7411-7415 (2006)

J.-F. Lutz, “Designing Polymer-based DNA Carriers for Non-Viral Gene Delivery: Have we Reached An Upper Performance Limit ?” in Gene Therapy: Prospective technology assessment in its societal context, 57-76 (2006)

J.-F. Lutz, R. Nehring, S. Pfeifer, Novel Organo-Soluble or Water-Soluble Copolymers Containing DNA Nucleobases, in Controlled/Living Radical Polymerization: From Synthesis to Materials, ACS Symposium Series, 944, 185-197 (2006)

J.-F. Lutz, Solution Self-Assembly of Tailor-made Macromolecular Building-Blocks Prepared by Controlled Radical Polymerization Techniques, Polymer International, 55, 979-993 (2006)

A. Laschewsky, S. Garnier, J. Kristen, M. Mertoglu, K. Skrabania, J.-F. Lutz, Comb-like polymeric surfactants by combining block and graft copolymer architectures, PMSE Preprints (American Chemical Society, Division of Polymeric Materials: Science and Engineering), 94, 307 (2006)

J.-F. Lutz, A. Hoth, Preparation of Ideal PEG Analogues with a Tunable Thermosensitivity by Controlled Radical Copolymerization of 2-(2-methoxyethoxy)ethyl Methacrylate and Oligo(ethylene glycol) Methacrylate, Macromolecules, 39, 893-896 (2006)


2005

J.-F. Lutz, A.F. Thünemann, K. Rurack, "DNA-like 'Melting' of Adenine- and Thymine-functionalized Synthetic Copolymers", Macromolecules, 38, 8124-8126 (2005).

H.G. Boerner, H. Rettig, M.G. J. ten Cate, J.-F. Lutz, E. Krause, "Macromolecular Chimera via Controlled Radical Polymerization Techniques", Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 46, 286-286 (2005)

J.-F. Lutz, S. Kubowicz, J.-F. Baussard, A.F. Thünemann, H. von Berlepsch, A. Laschewsky, "Multicompartment Micelles Obtained via the Self-assembly of a Well-Defined Triblock Macrosurfactant Prepared by RAFT Polymerization", Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 46, 297-298 (2005)

J.-F. Lutz, R. Nehring , A.F. Thünemann, "Solution Self-Assembly of Synthetic Copolymers Bearing Complementary Nucleic Acid Functionalities", Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 46, 397-398 (2005)

J.-F. Lutz, H.G. Boerner, K. Weichenhan, "Using 'Click' Chemistry for Post-Reacting Well-Defined Polymer Chains Prepared by Atom Transfer Radical Polymerization", Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 46, 486-487 (2005)

J.-F. Lutz, D. Schütt, S. Kubowicz, "Preparation of Well-Defined Diblock Copolymers with Short Polypeptide Segments via Polymerizations of N-Carboxyanhydrides", Macromolecular Rapid Communications, 26, 23-28 (2005)

J.-F. Lutz, K. Matyjaszewski "NMR Monitoring of Chain-End Functionality in Atom Transfer Radical Polymerization of Styrene" J. Polym. Sci., Part A: Polym. Chem, 43, 897-910 (2005)

W. Jakubowski, J.-F. Lutz, S. Slomkowski and K. Matyjaszewski "Block and Random Copolymers as Surfactants for Dispersion Polymerization. 1. Synthesis via Atom Transfer Radical Polymerization and Anionic Ring Opening Polymerization." J. Polym. Sci., Part A: Polym. Chem, 43, 1498-1510 (2005)

J.-F. Lutz, H. Boerner, K. Weichenhan, "Combining ATRP and Click Chemistry: a Versatile Method for Preparing End-Functional Polymers", Macromolecular Rapid Communications, 26,514-518 (2005)

J.-F. Lutz, R. Nehring , A.F. Thünemann, "Preparation by Controlled Radical Polymerization and Self-Assembly via Base-Recognition of Synthetic Polymers Bearing Complementary Nucleic Acids", J. Polym. Sci., Part A: Polym. Chem, 43, 4805-4818 (2005)

E. Mignard, J.-F. Lutz, T. Leblanc, K. Matyjaszewski, O. Guerret, W.F. Reed, "Kinetics and Molar Mass Evolution during Atom Transfer Radical Polymerization of n-Butyl Acrylate using Automatic Continuous Online Monitoring", in press macromolecules.

S. Kubowicz, J.-F. Baussard, J.-F. Lutz, A.F. Thünemann, H. von Berlepsch, A. Laschewsky, "Observation of Multicompartment Micelles Formed via Self-Assembly of Linear ABC Triblock Copolymers in Aqueous Medium" Angewandte Chemie International Edition, 44, 5262-5265 (2005)

J.-F. Lutz, A. Laschewsky, "Multicompartment Micelles: Did the Long-Standing Dream Become a Reality?" Macromolecular Chemistry and Physics, 206,813-817 (2005)

B. Kirci Denizli, J.-F. Lutz, L. Okrasa, T. Pakula, A. Güner, K. Matyjaszewski, "Properties of Well-defined Alternating and Random Copolymers of Methacrylates and Styrene Prepared by Controlled/Living Radical Polymerization", Journal of Polymer Science, Part A: Polymer Chemistry, 43, 3440-3446 (2005)